Nested Polymerase Chain Reaction with Specific Primers for Mucorales in the Serum of Patients with Hematological Malignancies
| Autor: | Hiroshi Yotsuyanagi, Mitsuhito Hirano, Toyotaka Kawamata, Kazuaki Yokoyama, Kaoru Uchimaru, Yoichi Imai, Yasunori Ota, Reina Takeda, Arinobu Tojo, Tomomi Takei, Tomohiko Koibuchi |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Mucorales Male Opportunistic infection 030106 microbiology Opportunistic Infections Polymerase Chain Reaction Serology 03 medical and health sciences 0302 clinical medicine Fatal Outcome Antigen medicine Humans Mucormycosis In patient 030212 general & internal medicine Aged DNA Primers biology business.industry General Medicine medicine.disease biology.organism_classification Virology Infectious Diseases Specific primers Hematologic Neoplasms Female business Nested polymerase chain reaction |
| Zdroj: | Japanese journal of infectious diseases. 72(3) |
| ISSN: | 1884-2836 |
| Popis: | Mucormycosis is an opportunistic infection occurring in immunocompromised hosts with hematological malignancies. Mortality due to mucormycosis in patients with hematological malignancies is high. However, the clinical symptoms of mucormycosis are poorly characterized, and diagnosis is difficult due to the lack of specific culture or serological markers or antigens. We present two cases in which nested polymerase chain reaction with specific primers was used in the serum of patients with hematological malignancies. |
| Databáze: | OpenAIRE |
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