Essential role of Wtip in mouse development and maintenance of the glomerular filtration barrier

Autor:	Sethu M. Madhavan, Martha Konieczkowski, Leslie A. Bruggeman, Megan DeWalt, Jane K. Nguyen, John F. O’Toole, John R. Sedor
Rok vydání:	2022
Předmět:	Podocytes Physiology Kidney Glomerulus Wilms Tumor Cytoskeletal Proteins Mice Proteinuria Glomerular Filtration Barrier Pregnancy Animals Guanine Nucleotide Exchange Factors Humans Female Kidney Diseases Co-Repressor Proteins
Zdroj:	American Journal of Physiology-Renal Physiology. 323:F272-F287
ISSN:	1522-1466 1931-857X
Popis:	Wilms' tumor interacting protein (Wtip) has been implicated in cell junction assembly and cell differentiation and interacts with proteins in the podocyte slit diaphragm, where it regulates podocyte phenotype. To define Wtip expression and function in the kidney, we created a
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c9e4dff3915486f5f5358be909a54a https://doi.org/10.1152/ajprenal.00051.2022 Zobrazit plný text záznamu