THE PHAGOCYTIC PROCESS OF HUMAN PERITONEAL MACROPHAGES IN CANCER OR UREMIA
| Autor: | Leif Athlin, L. Domellöf |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Functional impairment Adolescent Phagocytosis Immunology In Vitro Techniques Biology Neoplasms Internal medicine medicine Ascitic Fluid Humans Macrophage Ingestion Peritoneal Cavity Aged Uremia General Immunology and Microbiology Macrophages Cancer General Medicine Middle Aged medicine.disease Endocrinology Female Peritoneal Dialysis |
| Zdroj: | Acta Pathologica Microbiologica Scandinavica Series C: Immunology. :63-68 |
| ISSN: | 0108-0202 |
| Popis: | The ingestion and adherence components of the overall phagocytic process have been studied in human peritoneal macrophages (HPM) from cancer or uremic patients and compared with HPM from healthy controls. No difference was found in the studied functions between cancer patients and controls. However, HPM from uremic patients showed a highly significant impairment in the overall phagocytosis and the studied components of this function. In all groups the ingestion phase was significantly depressed after 24 hours of culture. Despite this functional impairment, the total phagocytic process was unchanged, owing to a significant increase in the adherence of test particles. |
| Databáze: | OpenAIRE |
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