Isosteric phosphonate pyrrolidine-based dinucleoside monophosphate analogues
Autor: | Vaclav Vanek, Markéta Rinnová, Milos Budesinsky, Ivana Kavenová, Ivan Rosenberg |
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Rok vydání: | 2003 |
Předmět: |
Poly U
Adenosine Binding Sites Pyrrolidines Stereochemistry Nucleotides Oligonucleotides Organophosphonates Stereoisomerism General Medicine Biochemistry Phosphonate Pyrrolidine chemistry.chemical_compound Hydroxyproline chemistry Nucleic acid Genetics Molecular Medicine Organic chemistry Indicators and Reagents Nucleoside Dinucleoside Phosphates |
Zdroj: | Nucleosides, nucleotidesnucleic acids. 22(5-8) |
ISSN: | 1525-7770 |
Popis: | A novel α- and β-configured pyrrolidine nucleoside phosphonates in adenine series were synthesized from trans-4-hydroxy-L-proline as starting material. d(ApA) analogues were also prepared and studied with respect to their hybridization properties with polyU. |
Databáze: | OpenAIRE |
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