Isosteric phosphonate pyrrolidine-based dinucleoside monophosphate analogues

Autor: Vaclav Vanek, Markéta Rinnová, Milos Budesinsky, Ivana Kavenová, Ivan Rosenberg
Rok vydání: 2003
Předmět:
Zdroj: Nucleosides, nucleotidesnucleic acids. 22(5-8)
ISSN: 1525-7770
Popis: A novel α- and β-configured pyrrolidine nucleoside phosphonates in adenine series were synthesized from trans-4-hydroxy-L-proline as starting material. d(ApA) analogues were also prepared and studied with respect to their hybridization properties with polyU.
Databáze: OpenAIRE
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