The role of wireless capsule endoscopy in investigating unexplained iron deficiency anemia after negative endoscopic evaluation of the upper and lower gastrointestinal tract
| Autor: | P. Gabriel, C. Kalantzis, Ian M. Gralnek, Periklis Apostolopoulos, Giannakoulopoulou E, Nikolaos Kalantzis, Christos Liatsos, Georgios Alexandrakis |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male medicine.medical_specialty Anemia Capsule Endoscopy Gastroenterology law.invention Capsule endoscopy law Internal medicine Intestine Small Biopsy Humans Medicine Prospective Studies Angiodysplasia Esophagus Prospective cohort study Aged Aged 80 and over Anemia Iron-Deficiency medicine.diagnostic_test business.industry Reproducibility of Results Middle Aged medicine.disease Barium meal Intestinal Diseases medicine.anatomical_structure Iron-deficiency anemia Female business Follow-Up Studies |
| Zdroj: | Endoscopy. 38:1127-1132 |
| ISSN: | 1438-8812 0013-726X |
| Popis: | Introduction: Despite undergoing standard endoscopic diagnostic evaluation with eosophagogastroduodenoscopy and ileocolonoscopy, up to 30% of patients with iron deficiency anemia (IDA) have no definitive diagnosis. The aim of this study was to prospectively investigate the role of wireless capsule endoscopy (WCE) in detecting lesions of the small bowel in patients with unexplained IDA after a negative endoscopic work-up. Patients and methods: Between 1 December 2003 and 31 December 2004, 253 consecutive patients who had been referred because of unexplained IDA underwent eosophagogastroduodenoscopy with small-bowel biopsies and ileocolonoscopy. Endoscopic and histological investigations were negative in 51 of these patients (20.2%) and WCE was performed. Air double-contrast enteroclysis was performed following WCE in all these patients. Results: Wireless capsule endoscopy revealed one or more small-bowel lesions that were considered to be a likely cause of the IDA in 29/51 patients (57%): angiodysplasias in twelve patients (23.5%), multiple jejunal and/or ileal ulcers in six patients (11.7%), multiple erosions in four patients (7.8%), a solitary ulcer in three patients (5.9%), polyps in two patients (3.9%), and tumors in two patients (3.9%). Enteroclysis revealed abnormal findings likely to cause IDA in only 6/51 patients (11.8%): multiple ileal ulcers in three patients (5.9%), tumors in two patients (3.9%), and polyps in one patient (1.9%) (enteroclysis vs. WCE, P |
| Databáze: | OpenAIRE |
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