Bacterial Colonization in Hidradenitis Suppurativa/Acne Inversa: A Cross-sectional Study of 50 Patients and Review of the Literature
| Autor: | Nikolaos G. Bonitsis, Holger Seltmann, Klaus Langner, Georgios Nikolakis, Ioannis Karagiannidis, Olivier Join-Lambert, Stefanos Bonovas, Thomas Wild, Silvia Zolke-Fischer, Aikaterini I. Liakou, Christos C. Zouboulis |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Dermatology Disease Severity of Illness Index 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Risk Factors Severity of illness Odds Ratio medicine Humans Hidradenitis suppurativa Prospective Studies Prospective cohort study Acne Chi-Square Distribution Bacteria business.industry Bacterial Infections General Medicine Odds ratio Middle Aged Prognosis medicine.disease Bacterial Load Hidradenitis Suppurativa Apocrine Glands Cross-Sectional Studies Logistic Models 030104 developmental biology Multivariate Analysis Female Anaerobic bacteria business Anaerobic exercise |
| Zdroj: | Acta Dermato Venereologica. 97:493-498 |
| ISSN: | 0001-5555 |
| DOI: | 10.2340/00015555-2591 |
| Popis: | It is unclear whether bacterial colonization in hidradenitis suppurativa/acne inversa (HS) comprises a primary cause, triggering factor or secondary phenomenon of the disease pathogenesis. Furthermore, the connection between certain bacterial species, the disease severity and its localization is unknown. Bacterial species were isolated from HS lesions to reveal a potential correlation with localization and disease severity. Ninety swab tests were prospectively obtained from 90 HS lesions of 50 consecutive patients. The material was cultured under aerobic and anaerobic conditions. The identified species were statistically correlated with Hurley stage and localization of the lesions. The most prevalent isolates were reported. Hurley stage significantly correlated with disease localization. Particular bacterial species were associated with "extended" disease and Hurley III stage with the detection of both aerobic and anaerobic bacteria and with a higher number of species. The presence of bacterial species is dependent on the local milieu, which correlates with the localization of the disease, its clinical manifestations and its extension. |
| Databáze: | OpenAIRE |
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