A Randomized Intervention Trial to Reduce the Lending of Used Injection Equipment Among Injection Drug Users Infected With Hepatitis C

Autor:	Elizabeth T. Golub, Sebastian Bonner, Jennifer V. Campbell, Farzana Kapadia, Thelma Thiel, Minya Pu, Mary H. Latka, Steffanie A. Strathdee, Dave L. Thomas, Micaela H. Coady, Richard S. Garfein, Holly Hagan
Rok vydání:	2008
Předmět:	Adult Male Relative risk reduction medicine.medical_specialty Randomization Research and Practice Adolescent education law.invention Risk-Taking Randomized controlled trial Behavior Therapy law Internal medicine Humans Medicine Needle Sharing Substance Abuse Intravenous Syringe business.industry Mentors Public Health Environmental and Occupational Health Hepatitis C Odds ratio medicine.disease United States Confidence interval Surgery Clinical trial ComputingMilieux_MANAGEMENTOFCOMPUTINGANDINFORMATIONSYSTEMS Female business Follow-Up Studies
Zdroj:	American Journal of Public Health. 98:853-861
ISSN:	1541-0048 0090-0036
DOI:	10.2105/ajph.2007.113415
Popis:	Objectives. We evaluated the efficacy of a peer-mentoring behavioral intervention designed to reduce risky distributive injection practices (e.g., syringe lending, unsafe drug preparation) among injection drug users with hepatitis C virus (HCV) infection. Methods. A randomized trial with a time-equivalent attention-control group was conducted among 418 HCV-positive injection drug users aged 18 to 35 years in 3 US cities. Participants reported their injection-related behaviors at baseline and at 3- and 6-month follow-ups. Results. Compared with the control group, intervention-group participants were less likely to report distributive risk behaviors at 3 months (odds ratio [OR]=0.46; 95% confidence interval [CI]=0.27, 0.79) and 6 months (OR=0.51; 95% CI=0.31, 0.83), a 26% relative risk reduction, but were no more likely to cite their HCV-positive status as a reason for refraining from syringe lending. Effects were strongest among intervention-group participants who had known their HCV-positive status for at least 6 months. Peer mentoring and self-efficacy were significantly increased among intervention-group participants, and intervention effects were mediated through improved self-efficacy. Conclusions. This behavioral intervention reduced unsafe injection practices that may propagate HCV among injection drug users.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b36fd16cfba3aac9ca9a0bcb43e0f1 https://doi.org/10.2105/ajph.2007.113415 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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