Effect of a chronotype-adjusted diet on weight loss effectiveness: A randomized clinical trial
| Autor: | M.C. Barberá Ortega, J.J. Hernández Morante, J.S. Galindo Muñoz, M. Gómez Gallego, I. Díaz Soler, C.M. Martínez Cáceres |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Waist Adolescent Psychological intervention 030209 endocrinology & metabolism Overweight Critical Care and Intensive Care Medicine law.invention Body Mass Index 03 medical and health sciences Young Adult 0302 clinical medicine Randomized controlled trial Double-Blind Method Weight loss law Internal medicine Weight Loss medicine Humans Aged Chronobiology Phenomena Chronobiology 030109 nutrition & dietetics Nutrition and Dietetics business.industry Chronotype Middle Aged medicine.disease Obesity Diet Treatment Outcome Female medicine.symptom business Follow-Up Studies |
| Zdroj: | Clinical nutrition (Edinburgh, Scotland). 39(4) |
| ISSN: | 1532-1983 |
| Popis: | Summary Background & aims The alteration of normal biological rhythms, also known as chronodisruption, may be associated with obesity development. For instance, those subject with preference for vespertinity seem to be prone to develop obesity. However, the current hypocaloric dietary treatment of obesity does not take into account these aspects. Therefore, the objective of this trial was to evaluate whether a diet adjusted to patient's chronotype is more effective that the current dietary recommendations. Methods 209 subjects take part on a 3 month randomized, double-blind trial. 104 subjects followed a typical hypocaloric dietary treatment and the other 105 subjects undergone a diet with a daily caloric distribution adjusted to their chronotype. There were no sex or age differences between groups. Results Baseline characteristics were similar in both groups. Dropout rate was also similar in both interventions (p = 0.683). Although both groups improved their anthropometrical parameters, the chronotype-adjusted diet group achieved a statistically significant greater reduction in percentage of total body weight loss (%TWL), BMI and waist circumference than the control group (p Conclusions This randomized trial has demonstrated for the first time that in overweight/obese subjects, a chronotype-adjusted diet is more effective than the traditional hypocaloric dietary treatment, at least regarding the anthropometrical parameters. Further research will confirm if this intervention is also more effective in the long term. Trial registration NCT-ID: #NCT03755674, (available at: http://www.clinicaltrials.gov ). |
| Databáze: | OpenAIRE |
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