Transient changes of serum lipoprotein(a) as an acute phase protein
| Autor: | Satoshi Maeda, Kazuhiko Makino, Masaka Kawade, Akira Abe, Akio Noma, Mitsuru Seishima |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
medicine.medical_specialty
Time Factors Lipoproteins Myocardial Infarction Alpha (ethology) Internal medicine Tissue damage medicine Humans Myocardial infarction chemistry.chemical_classification biology business.industry Haptoglobin Acute-phase protein Plasminogen Lipoprotein(a) medicine.disease Surgery Endocrinology chemistry Surgical Procedures Operative biology.protein Cardiology and Cardiovascular Medicine business Glycoprotein Acute-Phase Proteins Lipoprotein |
| Zdroj: | Atherosclerosis. 78:145-150 |
| ISSN: | 0021-9150 |
| DOI: | 10.1016/0021-9150(89)90218-9 |
| Popis: | Serum lipoprotein(a) (Lp(a)) was serially determined after acute attacks of myocardial infarction and after surgical operations. Acute phase proteins, such as C-reactive protein, alpha 1-acid glycoprotein, alpha 1-antitrypsin and haptoglobin, increased rapidly and markedly after the episodes. Initial values of serum Lp(a) concentrations were almost the same in both groups. Increases in serum Lp(a) levels were also observed during the first few days, with a return to the initial levels after more than 1 month. The periods for reaching maximal levels of acute phase proteins were similar in both groups of patients. On the contrary, the period required for Lp(a) to reach the maximal level in the myocardial infarction group was significantly longer than in the post-operative group. The present study suggests that Lp(a) has the characteristics of an acute phase reactant and may play an important role in recovery from tissue damage. |
| Databáze: | OpenAIRE |
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