Universal versus selective screening for gestational diabetes mellitus among antenatal clinic attendees in Abakaliki: using the one-step 75 gram oral glucose tolerance test
| Autor: | Ikechukwu Bo Dimejesi, Oghenevwogaga Obukohwo Edenya, RC Onoh, Silas Alegu Nwali, Vitus Okwuchukwu Obi, Sunday Emmanuel Jombo |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Multivariate analysis endocrine system diseases Reproductive medicine Prevalence Nigeria Oral glucose tolerance test Logistic regression Sensitivity and Specificity Gestational diabetes mellitus Selective screening Pregnancy Risk Factors Statistical significance Medicine Humans Mass Screening One-step Risk factor business.industry Obstetrics Research Obstetrics and Gynecology nutritional and metabolic diseases Prenatal Care Gynecology and obstetrics Glucose Tolerance Test Middle Aged medicine.disease Gestational diabetes Universal screening Diabetes Gestational Cross-Sectional Studies Hyperglycemia RG1-991 Gestation Female business |
| Zdroj: | BMC Pregnancy and Childbirth, Vol 21, Iss 1, Pp 1-8 (2021) BMC Pregnancy and Childbirth |
| ISSN: | 1471-2393 |
| Popis: | AimTo compare universal screening with selective risk factor based screening for GDM, using the one-step 75 g oral glucose tolerance test (OGTT).Materials and methodA cross-sectional, comparison between universal and selective risk factor based screening for GDM, among 400 antenatal care clients at Alex-Ekwueme Federal University Teaching Hospital Abakaliki (AE-FUTHA). All the participants had 75 g OGTT at 24–28 weeks of gestation and risk factor screening for GDM. All 400 participants formed the universal group while participants with one or more of the considered risk factors formed the selective risk factor group.Data were analyzed using IBM SPSS version 20. Statistical comparison was done using t- test for continuous variables. Logistics regression was used to determine the level of associations of the independent predictors for hyperglycemia. Level of significance was set atP ResultsThe point prevalence of GDM using universal and selective screening were 11.51 and 7.93% respectively, giving a selective screening miss rate of 31.11%. The sensitivity, specificity, positive predictive value and negative predictive value were 73.58, 48.82, 19.12 and 92.51% respectively for the selective risk factor based screening compared to universal screening.On multivariate analysis; age ≥ 35 years, weight ≥ 90 kg, history of previous GDM and hypertension were significantly related to the development of hyperglycemia.ConclusionSelective risk factor based screening missed 31.11% of patients with GDM when compare to Universal screening with one step 75 g OGTT. Universal screening for GDM using the one step 75 g OGTT is recommended for pregnant women and more studies are needed to compare pregnancy outcomes for pregnant women diagnosed with GDM with and without risk factors. |
| Databáze: | OpenAIRE |
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