Modulation of pulse propagation and blood flow via cuff inflation—new distal insights
| Autor: | Erik Bresch, Lars Schmitt, Jens Muehlsteff, Gerrit Jan Noordergraaf, Laura I. Bogatu, Hendrikus H. M. Korsten, Massimo Mischi, Igor Wilhelmus Franciscus Paulussen, Simona Turco, Pierre Hermanus Woerlee, Arthur Bouwman |
|---|---|
| Přispěvatelé: | Center for Care & Cure Technology Eindhoven, Biomedical Diagnostics Lab, Eindhoven MedTech Innovation Center, Signal Processing Systems, EAISI Health, Electrical Engineering |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Mean arterial pressure Pulse transit time Blood Pressure TP1-1185 Pulse Wave Analysis Pulse arrival time Biochemistry Article Analytical Chemistry Occlusion-based perturbation Heart Rate Internal medicine Functional hemodynamic monitoring Occlusion medicine Flow modulation Humans Electrical and Electronic Engineering Instrumentation Pulse (signal processing) business.industry Chemical technology Blood Pressure Determination Cuff-based measurement Arteries Blood flow Atomic and Molecular Physics and Optics Compliance (physiology) Pulse propagation modulation medicine.anatomical_structure Blood pressure Blood pressure cuff Cuff Cardiology business Artery |
| Zdroj: | Sensors, 21(16):5593. Multidisciplinary Digital Publishing Institute (MDPI) Sensors Volume 21 Issue 16 Sensors (Basel, Switzerland) Sensors, Vol 21, Iss 5593, p 5593 (2021) |
| ISSN: | 1424-8220 |
| Popis: | In standard critical care practice, cuff sphygmomanometry is widely used for intermittent blood pressure (BP) measurements. However, cuff devices offer ample possibility of modulating blood flow and pulse propagation along the artery. We explore underutilized arrangements of sensors involving cuff devices which could be of use in critical care to reveal additional information on compensatory mechanisms. In our previous work, we analyzed the response of the vasculature to occlusion perturbations by means of observations obtained non-invasively. In this study, our aim is to (1) acquire additional insights by means of invasive measurements and (2) based on these insights, further develop cuff-based measurement strategies. Invasive BP experimental data is collected downstream from the cuff in two patients monitored in the OR. It is found that highly dynamic processes occur in the distal arm during cuff inflation. Mean arterial pressure increases in the distal artery by 20 mmHg, leading to a decrease in pulse transit time by 20 ms. Previous characterizations neglected such distal vasculature effects. A model is developed to reproduce the observed behaviors and to provide a possible explanation of the factors that influence the distal arm mechanisms. We apply the new findings to further develop measurement strategies aimed at acquiring information on pulse arrival time vs. BP calibration, artery compliance, peripheral resistance, artery-vein interaction. |
| Databáze: | OpenAIRE |
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