Influence of Electrical Stimulation of the Hypothalamus on Ovarian Steroidogenesis in Hypophysectomized and Adrenalectomized Rats
| Autor: | Masazumi Kawakami, Takayuki Sato, M. Kondo, Edashige N, K. Seto, H. Kaba, H. Saito, Takeshima Y |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
Hypophysectomy medicine.drug_class Endocrinology Diabetes and Metabolism medicine.medical_treatment Hypothalamus Stimulation Ovary Biology Endocrinology Arcuate nucleus Internal medicine Adrenal Glands Internal Medicine medicine Animals Progesterone Arc (protein) Adrenalectomy Arcuate Nucleus of Hypothalamus Estrogens General Medicine Electric Stimulation 20-alpha-Dihydroprogesterone Rats medicine.anatomical_structure Ventromedial Hypothalamic Nucleus Estrogen Hypothalamic Area Lateral Pituitary Gland Female |
| Zdroj: | Experimental and Clinical Endocrinology & Diabetes. 95:259-261 |
| ISSN: | 1439-3646 0947-7349 |
| Popis: | The effects of electrical stimulation of the lateral hypothalamic area (LHA), periventricular arcuate nucleus (ARC) and ventromedial hypothalamic nucleus (VMH) on the rates of 14C transfer from 14C-1 acetate into ovarian steroids in ovarian slices of hypophysectomized and adrenalectomized (H-A) rats were investigated. The 14C transfer rates into estrogen and 20 alpha-hydroxypregn-4-en-3-one (20 alpha-OH-P) were decreased by LHA stimulation. The stimulation of the ARC and VMH increased the rates of 14C transfer into estrogen, progesterone and 20 alpha-OH-P. From these results, it might be suggested that these hypothalamic structures were involved in the regulation of ovarian steroidogenesis without participation of the pituitary and adrenal. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|