Micronutrient Depletion in Heart Failure: Common, Clinically Relevant and Treatable
| Autor: | Natasa Cvetinovic, Wolfram Doehner, Stephan von Haehling, Goran Loncar, Jerneja Farkas, Mitja Lainscak, Andjelka M. Isakovic |
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| Rok vydání: | 2019 |
| Předmět: |
Chronic condition
medicine.medical_specialty Micronutrient deficiency trace elements Context (language use) Review 030204 cardiovascular system & hematology Catalysis Cachexia lcsh:Chemistry Inorganic Chemistry 03 medical and health sciences 0302 clinical medicine iron medicine Humans 030212 general & internal medicine Physical and Theoretical Chemistry Intensive care medicine lcsh:QH301-705.5 Molecular Biology Spectroscopy Heart Failure business.industry Organic Chemistry Avitaminosis General Medicine Vitamins heart failure micronutrients vitamins medicine.disease Micronutrient Comorbidity 3. Good health Computer Science Applications lcsh:Biology (General) lcsh:QD1-999 Sarcopenia Heart failure business |
| Zdroj: | International Journal of Molecular Sciences International Journal of Molecular Sciences, Vol 20, Iss 22, p 5627 (2019) |
| ISSN: | 1422-0067 |
| Popis: | Heart failure (HF) is a chronic condition with many imbalances, including nutritional issues. Next to sarcopenia and cachexia which are clinically evident, micronutrient deficiency is also present in HF. It is involved in HF pathophysiology and has prognostic implications. In general, most widely known micronutrients are depleted in HF, which is associated with symptoms and adverse outcomes. Nutritional intake is important but is not the only factor reducing the micronutrient availability for bodily processes, because absorption, distribution, and patient comorbidity may play a major role. In this context, interventional studies with parenteral micronutrient supplementation provide evidence that normalization of micronutrients is associated with improvement in physical performance and quality of life. Outcome studies are underway and should be reported in the following years. |
| Databáze: | OpenAIRE |
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