Near-field impedance accurately distinguishes among pericardial, intracavitary, and anterior mediastinal position
| Autor: | Mathews John, Abdi Rasekh, Brian Greet, Mohammad Saeed, Mehdi Razavi, Anand V. Ganapathy, David Burkland |
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| Rok vydání: | 2017 |
| Předmět: |
Epicardial Mapping
Male medicine.medical_specialty Percutaneous Heart Ventricles medicine.medical_treatment Catheter ablation 030204 cardiovascular system & hematology Inferior vena cava 03 medical and health sciences 0302 clinical medicine Physiology (medical) Internal medicine Electric Impedance medicine Animals 030212 general & internal medicine Major complication Sheep business.industry Mediastinum Arrhythmias Cardiac Catheter medicine.anatomical_structure medicine.vein Ventricle Catheter Ablation Cardiology Cardiology and Cardiovascular Medicine Complication Anatomical compartment business Pericardium |
| Zdroj: | Journal of Cardiovascular Electrophysiology. 28:1492-1499 |
| ISSN: | 1045-3873 |
| Popis: | Introduction Epicardial catheter ablation is increasingly used to treat arrhythmias with an epicardial component. Nevertheless, percutaneous epicardial access remains associated with a significant risk of major complications. Developing a technology capable of confirming proper placement within the pericardial space could decrease complication rates. The purpose of this study was to examine differences in bioimpedance among the pericardial space, anterior mediastinum, and right ventricle. Methods An ovine model (n = 3) was used in this proof-of-concept study. A decapolar catheter was used to collect bipolar impedance readings; data were collected between each of 5 electrode pairs of varying distances. Data were collected from 3 test regions: the pericardial space, anterior mediastinum, and right ventricle. A control region in the inferior vena cava was used to normalize the data from the test regions. Analysis of variance was used to test for differences among regions. Results A total of 10 impedance values were collected in each animal between each of the 5 electrode pairs in the 3 test regions (n = 340) and the control region (n = 145). The average normalized impedance values were significantly different among the pericardial space (1.760 ± 0.370), anterior mediastinum (3.209 ± 0.227), and right ventricle (1.024 ± 0.207) (p |
| Databáze: | OpenAIRE |
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