In vitro antistreptococcal activity of the potassium-sparing diuretics amiloride and triamterene
| Autor: | G Sampaoli, G Turchetti, Luciano Galeazzi, Sergio Giunta, Giuseppe Groppa |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Pharmacology
Triamterene Chemistry medicine.drug_class Ionophore Streptococcus Biological activity Microbial Sensitivity Tests Antimicrobial In vitro Amiloride Infectious Diseases Biochemistry Species Specificity Potassium-sparing diuretic medicine Pharmacology (medical) Antibacterial agent medicine.drug Research Article |
| Zdroj: | Antimicrobial agents and chemotherapy. 28(3) |
| ISSN: | 0066-4804 |
| Popis: | The ionophore antimicrobial agents provide evidence that perturbations of the electrolyte balance of bacterial cells exert a growth-inhibitory activity. Several drugs acting on animal cell membranes have also been shown to be active on bacterial cells. In this paper, we report preliminary susceptibility studies showing that the class of potassium-sparing diuretics acting directly on monovalent cation fluxes on animal cells possesses a selective growth-inhibitory activity on hemolytic streptococci. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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