A Portable Wireless Urine Detection System With Power-Efficient Electrochemical Readout ASIC and ABTS-CNT Biosensor for UACR Detection

Autor: Meng-Dar Shieh, Ju Yi Chen, Yi-Chieh Wei, Shuenn-Yuh Lee, Hao-Yun Lee, Peng-Wei Huang, Zhan-Xian Liao, Chia Yu Lin, Yi-Ting Hsieh, Ding-Siang Ciou
Rok vydání: 2021
Předmět:
Zdroj: IEEE transactions on biomedical circuits and systems. 15(3)
ISSN: 1940-9990
Popis: This work presents a portable wireless urine detection system which consists of an electrochemical readout application specific integrated circuit (ASIC) and a biosensor composed of 2, 2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) and carbon nanotube (ABTS-CNT) for the detection of urine albumin-to-creatinine ratio (UACR). The ASIC includes a potentiostat, a digital circuitry and a power management circuit which can perform electrochemistry techniques with a dual-channel screen-printing carbon electrode (SPCE). Electrochemical experiments on the proposed biosensor (SPCE|ABTS-CNT|Nafion) have revealed promising sensing characteristics for creatinine and human serum albumin detection. Practical urine tests has demonstrated the capability of the proposed urine detection system for UACR detection with both the power-efficient readout ASIC and the ABTS-CNT biosensor. A user-friendly prototype has also been designed which can be useful for either personal health administrationor homecare.
Databáze: OpenAIRE