Synthesis and Crystallographic Characterization of a Maleimide Derivative of Tryptamine
| Autor: | Grégoire Rondelet, Jean Dubois, Melwin Colaço, Johan Wouters |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Tryptamine
Materials science General Chemical Engineering 010402 general chemistry 01 natural sciences Inorganic Chemistry chemistry.chemical_compound maleic anhydride lcsh:QD901-999 General Materials Science mechanosynthesis Maleimide powder X-ray diffraction 010405 organic chemistry Final product Maleic anhydride single-crystal structure Condensed Matter Physics grinding 0104 chemical sciences Crystallography chemistry Yield (chemistry) Mechanosynthesis lcsh:Crystallography Derivative (chemistry) tryptamine |
| Zdroj: | Crystals, Vol 6, Iss 11, p 153 (2016) Dubois, J, Colaço, M, Rondelet, G & Wouters, J 2016, ' Synthesis and Crystallographic Characterization of a Maleimide Derivative of Tryptamine ', Crystals, vol. 6 . https://doi.org/10.3390/cryst6110153 |
| ISSN: | 2073-4352 |
| Popis: | While mechanosynthesis of the target compound, 1-[2-(1H-indol-3-yl)-ethyl]-pyrrole-2,5-dione, C14 H12 N2 O2, did not yield the desired product, it instead resulted in an open intermediate. On the other hand, synthesis starting from the activated maleic anhydride yielded the final maleimide compound. The outcome of the mechanosynthesis has been evaluated by powder X-ray diffraction, and structures of both the final product and open intermediate have been confirmed using single-crystal crystallography. While mechanosynthesis of the target compound, 1-[2-(1H-indol-3-yl)-ethyl]-pyrrole-2,5-dione, C14 H12 N2 O2, did not yield the desired product, it instead resulted in an open intermediate. On the other hand, synthesis starting from the activated maleic anhydride yielded the final maleimide compound. The outcome of the mechanosynthesis has been evaluated by powder X-ray diffraction, and structures of both the final product and open intermediate have been confirmed using single-crystal crystallography. |
| Databáze: | OpenAIRE |
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