Thermic effect of feeding carbohydrate, fat, protein and mixed meal in lean and obese subjects
Autor: | J K Wales, R Swaminathan, Rfgj King, J. Holmfield, RA Siwek, M Baker |
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Rok vydání: | 1985 |
Předmět: |
Adult
Male medicine.medical_specialty Time Factors Medicine (miscellaneous) Calorimetry Mixed meal Internal medicine Dietary Carbohydrates Medicine Fatty meal Ingestion Humans Obesity Meal Nutrition and Dietetics Gastric emptying business.industry digestive oral and skin physiology Body Weight Carbohydrate Middle Aged Dietary Fats Endocrinology Glucose Gastric Emptying Basal metabolic rate Obese subjects Female Basal Metabolism Dietary Proteins business Body Temperature Regulation |
Zdroj: | The American journal of clinical nutrition. 42(2) |
ISSN: | 0002-9165 |
Popis: | The thermic effect of 1.67 MJ (400 kcal) of carbohydrate (glucose), fat, protein and mixed meal were examined in 11 lean and 11 obese subjects by indirect calorimetry. The changes in metabolic rate in response over 90 min period (30-120 min after the meal) to the different meals were compared with that seen after a similar volume of low calorie drink. The thermic effects of glucose and protein were not significantly different between lean and obese subjects. Obese subjects showed very little increase in metabolic rate following ingestion of fat (-0.9 +/- 2.0%, mean +/- SEM) and this was significantly different from that seen in lean subjects (14.4 +/- 3.4%). The thermogenic response to mixed meal was also significantly lower in obese subjects when expressed as percentage change (12.9 +/- 2.3% compared to 25.0 +/- 4.8%). There was no evidence for delay in gastric emptying times for glucose and fatty meal in the six obese subjects in whom these were measured. We conclude that obese subjects show a reduced thermogenic response to fat. |
Databáze: | OpenAIRE |
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