Presenting symptoms and functional outcome of chronic subdural hematoma patients
| Autor: | Bram Jacobs, Jurre Blaauw, Heleen M. den Hertog, Rob J. M. Groen, Niels A van der Gaag, Ghislaine A Meelis, Hester F. Lingsma, Korné Jellema, Joukje van der Naalt, Kuan Hua Kho |
|---|---|
| Přispěvatelé: | Public Health, Molecular Neuroscience and Ageing Research (MOLAR) |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
cognition
Male medicine.medical_specialty presenting symptoms Glasgow Outcome Scale Signs and symptoms functional outcome Chronic subdural hematoma Internal medicine INJURY medicine Humans In patient Glasgow Coma Scale RECURRENCE Aged Retrospective Studies business.industry Confounding Cognition General Medicine REVERSIBLE DEMENTIA MILD Outcome (probability) Treatment Outcome Neurology chronic subdural hematoma Hematoma Subdural Chronic Neurology (clinical) business |
| Zdroj: | Acta Neurologica Scandinavica, 145(1), 38-46. Wiley-Blackwell Publishing Ltd Acta neurologica Scandinavica, 145(1), 38-46. Wiley Acta Neurologica Scandinavica, 145(1), 38-46. WILEY |
| ISSN: | 0001-6314 |
| Popis: | Background: Patients with chronic subdural hematoma (CSDH) can present with a variety of signs and symptoms. The relationship of these signs and symptoms with functional outcome is unknown. Knowledge of these associations might aid clinicians in the choice to initiate treatment and may allow them to better inform patients on expected outcomes. Objective: To investigate if presenting signs and symptoms influence functional outcome in patients with CSDH. Methods: We conducted a retrospective analysis of consecutive CSDH patients in three hospitals. Glasgow Outcome Scale Extended (GOS-E) scores were obtained from the first follow-up visit after treatment. An ordinal multivariable regression analysis was performed, to assess the relationship between the different signs and symptoms on the one hand and functional outcome on the other adjusted for potential confounders. Results: We included 1,307 patients, of whom 958 (73%) were male and mean age was 74 (SD ± 11) years. Cognitive complaints were associated with lower GOS-E scores at follow-up (aOR 0.7, 95% CI: 0.5 – 0.8) Headache and higher Glasgow Coma Scale (GCS) scores were associated with higher GOS-E scores. (aOR 1.9, 95% CI: 1.5–2.3 and aOR 1.3, 95% CI: 1.2–1.4). Conclusion: Cognitive complaints are independently associated with worse functional outcome, whereas headache and higher GCS scores are associated with better outcome. The increased probability of unfavorable outcome in patients with CSDH who present with cognitive complaints favors a more prominent place of assessing cognitive status at diagnosis. |
| Databáze: | OpenAIRE |
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