Expression and Functional Analysis of cofilin1-like in Craniofacial Development in Zebrafish

Autor:	Sil Jin, Haewon Jeon, Chong Pyo Choe
Rok vydání:	2022
Zdroj:	Development & Reproduction. 26:23-36
ISSN:	2465-9541 2465-9525
DOI:	10.12717/dr.2022.26.1.23
Popis:	Pharyngeal pouches, a series of outgrowths of the pharyngeal endoderm, are a key epithelial structure governing facial skeleton development in vertebrates. Pouch formation is achieved through collective cell migration and rearrangement of pouch-forming cells controlled by actin cytoskeleton dynamics. While essential transcription factors and signaling molecules have been identified in pouch formation, regulators of actin cytoskeleton dynamics have not been reported yet in any vertebrates. Cofilin1-like (Cfl1l) is a fish-specific member of the Actin-depolymerizing factor (ADF)/Cofilin family, a critical regulator of actin cytoskeleton dynamics in eukaryotic cells. Here, we report the expression and function of
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758723d318464d00f0c25aad15c29c21 https://doi.org/10.12717/dr.2022.26.1.23 Zobrazit plný text záznamu