Gastric Acid Secretion, Mucus Concentration and Ulceration Following Orogastic Feeding of Cannabis Sativa to Albino Wistar Rats

Autor: OO Okwari, AO Aya, AO Obembe
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Global Journal of Medical Sciences; Vol 10, No 1-2 (2011); 37-42
ISSN: 1596-2911
Popis: This study was carried out to evaluate the effect of consumption (ingestion) of Cannabis sativa on the gastrointestinal tract using mucus concentration, acid secretion and ulceration in animal (rats) model as indices. Three groups of six (6) rats each were used. The control group were fed on rat chow only while another group were fed on low dose of Cannabis sativa 0.5gm/100g body weight and another group were fed on high dose of Cannibis sativa 0.8mg/100g body weight for 28 days respectively and allowed free access to food and water. At the end of 28 days, the results showed that the acid secretion in the high dose group was significantly (P
Databáze: OpenAIRE