High implantation and pregnancy rates with testicular sperm extraction and intracytoplasmic sperm injection in obstructive and non-obstructive azoospermia
| Autor: | Suat Özgür, Basak Balaban, Senai Aksoy, Kutay Biberoglu, Murat Taşdemir, Alp Nuhoglu, Semra Kahraman, T. Evrenkaya, Cengiz Alatas, Pierre Vanderzwalmen, Robert Schoysman, M. Nijs |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Male
endocrine system Cytoplasm Microinjections medicine.medical_treatment Obstructive azoospermia Fertilization in Vitro Suction urologic and male genital diseases Intracytoplasmic sperm injection Andrology Reproductive Techniques Pregnancy Testis medicine Humans reproductive and urinary physiology Azoospermia urogenital system business.industry Rehabilitation Pregnancy Outcome Obstetrics and Gynecology Oligospermia medicine.disease Embryo Transfer Sperm Spermatozoa Testicular sperm extraction Embryo transfer Pregnancy rate Reproductive Medicine Sperm Retrieval Female business |
| Zdroj: | Human reproduction (Oxford, England). 11(3) |
| ISSN: | 0268-1161 |
| Popis: | Thirty-two infertile couples with obstructive and non-obstructive azoospermia were included in this study. Testicular sperm extraction (TESE) was performed in 16 obstructive azoospermic cases where microsurgical sperm aspiration (MESA) or percutaneous sperm aspiration (PESA) were impossible because of totally destroyed epididymis and 16 non-obstructive azoospermia cases with severe spermatogenetic defect where the testicles were the only source of sperm cells. A total of 288 oocytes was obtained from 32 females and 84% were injected. The fertilization rates (FR) with 2 pronuclei (PN) and cleavage rate were 50.8 and 68.2% respectively. A total of 15 pregnancies was achieved (53% per embryo transfer), nine from the obstructive and six from the non-obstructive group. Four pregnancies resulted in clinical abortion (26.6%). The ongoing pregnancy rate was 39.2% per embryo transfer (ET) and 34.3% per started cycle. A high implantation rate was also achieved (26.6% in non-obstructive and 30% in obstructive azoospermia group). Using testicular spermatozoa in combination with ICSI in both obstructive and non-obstructive azoospermic groups, high implantation and pregnancy rates can be achieved. |
| Databáze: | OpenAIRE |
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