Effect of ruthenium red upon Ca2+ and Mn2+ uptake in Saccharomyces cerevisiae. Comparison with the effect of La3+
| Autor: | R.H.M. van der Pal, P.J.M. Belde, Alexander P.R. Theuvenet, G.W.F.H. Borst-Pauwels, P.H.J. Peters |
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| Rok vydání: | 1987 |
| Předmět: |
inorganic chemicals
Ruthenium red Inorganic chemistry Biophysics chemistry.chemical_element Calcium ion transport Saccharomyces cerevisiae Calcium Biochemistry Ruthenium Divalent chemistry.chemical_compound Lanthanum Cations otorhinolaryngologic diseases Incubation Ion transporter chemistry.chemical_classification Manganese Calcium Radioisotopes Cell Biology Ruthenium Red Manganese ion transport Kinetics chemistry Potassium cardiovascular system Efflux |
| Zdroj: | Biochimica et Biophysica Acta (BBA) - Biomembranes. 902:19-23 |
| ISSN: | 0005-2736 |
| DOI: | 10.1016/0005-2736(87)90131-3 |
| Popis: | The initial rate of both Ca2+ and Mn2+ uptake is inhibited by ruthenium red to about the same extent as by equivalent concentrations of La3+. The inhibition of Ca2+ uptake, however, is relieved during further incubation with ruthenium red. On preincubating the cells with ruthenium red even a stimulation of divalent cation uptake can be found. Relieve of the inhibition of divalent cation uptake is accompanied by K+ efflux. Both ruthenium red and La3+ displace Ca2+ very effectively from binding sites at the cell surface. The inhibition of initial Ca2+ uptake is accompanied by a reduction in the binding of Ca2+. |
| Databáze: | OpenAIRE |
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