Recurrence and survival rates in node negative patients after sentinel node biopsy for early-stage vulva cancer – A nationwide study
| Autor: | Jann Mortensen, Ligita Paskeviciute Froeding, Isa Niemann, Ingrid Thranov, Vibeke Zobbe, Elisabeth Kristensen, Claus Høgdall, Ole Mathiesen, Tine H. Schnack, Gitte Ørtoft |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
0301 basic medicine medicine.medical_specialty Survival Denmark Sentinel Node procedure Vulva 03 medical and health sciences 0302 clinical medicine Biopsy medicine Humans Prospective Studies Registries Stage (cooking) Isolated groin recurrence Aged Neoplasm Staging Aged 80 and over Vulvar Neoplasms medicine.diagnostic_test Groin Sentinel Lymph Node Biopsy business.industry Incidence (epidemiology) Obstetrics and Gynecology Cancer Middle Aged Sentinel node medicine.disease Surgery Clinical trial Vulva cancer 030104 developmental biology medicine.anatomical_structure Oncology Lymphatic Metastasis 030220 oncology & carcinogenesis Carcinoma Squamous Cell Female Neoplasm Recurrence Local Sentinel Lymph Node business |
| Zdroj: | Froeding, L P, Høgdall, C, Kristensen, E, Zobbe, V, Niemann, I, Ørtoft, G, Thranov, I, Mathiesen, O, Mortensen, J & Schnack, T H 2020, ' Recurrence and survival rates in node negative patients after sentinel node biopsy for early-stage vulva cancer – A nationwide study ', Gynecologic Oncology, vol. 156, no. 1, pp. 124-130 . https://doi.org/10.1016/j.ygyno.2019.10.024 |
| ISSN: | 0090-8258 |
| DOI: | 10.1016/j.ygyno.2019.10.024 |
| Popis: | Objective: The sentinel node (SN) procedure is adopted in selected patients with early-stage vulva cancer (VC) in Denmark. Due to the low incidence of VC, large population-based studies on the safety of SN outside multicenter clinical trials are lacking. The current study evaluated the risk of recurrence and survival in SN- negative VC patients. Methods: Nationwide data was collected and registered prospectively in the Danish Gynecologic Cancer Database from January 2011 to July 2017. Patients with clinically stage IB-II unifocal vulva squamous cell carcinoma, tumor |
| Databáze: | OpenAIRE |
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