Neonatal Rectal Colonization with Malassezia furfur

Autor: Noni E. MacDonald, Andrew M. Mackenzie, Gil J Gross
Jazyk: angličtina
Rok vydání: 1992
Předmět:
Zdroj: Canadian Journal of Infectious Diseases, Vol 3, Iss 1, Pp 9-13 (1992)
ISSN: 1180-2332
Popis: Malassezia furfurandCandida albicansare fungal pathogens which have been recognized with increasing frequency as agents of mortality and serious morbidity in neonatal intensive care unit patients. A longitudinal study of oral, rectal and umbilical colonization by these organisms of newborns admitted to a neonatal intensive care unit within 24 h of birth was undertaken. Of 71 infants followed for a minimum of 10 days, 24 were colonized withM furfurand 12 withC albicansduring the first 10 days of life. The lower gastrointestinal tract was found to be the most common colonization site for both organisms. Statistically significant (PM furfurandC albicansare common colonizing organisms in a neonatal intensive care unit setting and are most frequently harboured in the lower gastrointestinal tract.M furfur, recently implicated as a systemic pathogen in this population, has not been previously recognized as a gastrointestinal commensal organism. The relationship between colonization and invasive fungal disease, and potential roles for preventive strategies, remain to be elucidated.
Databáze: OpenAIRE