Supplementary Tables 1 - 3 from Targeting Activated Akt with GDC-0068, a Novel Selective Akt Inhibitor That Is Efficacious in Multiple Tumor Models

Autor: Kui Lin, Lori S. Friedman, Elizabeth Punnoose, Marcia Belvin, Jeffrey J. Wallin, Nicholas J. Skelton, Hartmut Koeppen, Bianca M. Liederer, Stefan Gross, Tyler Risom, Leslie B. Lee, Robert Kassees, Rebecca Hong, Zhengyu Guan, Heidi Savage, Jason Oeh, Michael Degtyarev, Brian B. Lee, Michelle A. Nannini, Deepak Sampath, Jie Lin
Rok vydání: 2023
Popis: XLSX file - 74K, Table S1. Enzymatic potency, selectivity and cellular potency of GDC-0068 Table S2. GDC-0068 IC50 profile on cell viability and genetic background of cancer cell lines Table S3. Maximum percent body weight changes of mice treated with GDC-0068 single agent and in combination with chemotherapeutic agents
Databáze: OpenAIRE