Evaluating Changes in Symptoms During Acute Alcohol Withdrawal
| Autor: | Samuel C. Kaim, Palo Alto, C. James Klett, Perry Point, Eugene M. Caffey, Leo E. Hollister |
|---|---|
| Rok vydání: | 1971 |
| Předmět: |
Male
Chlorpromazine Placebo Psychoses Alcoholic Chlordiazepoxide Placebos Arts and Humanities (miscellaneous) Seizures Rating scale Humans Medicine Thiamine Psychiatric Status Rating Scales Hydroxyzine Clinical Trials as Topic business.industry Incidence (epidemiology) Substance Withdrawal Syndrome Affect Alcoholism Psychiatry and Mental health Anesthesia Delirium Female medicine.symptom business medicine.drug |
| Zdroj: | Archives of General Psychiatry. 24:174 |
| ISSN: | 0003-990X |
| DOI: | 10.1001/archpsyc.1971.01750080078013 |
| Popis: | Male patients experiencing the symptoms of acute alcohol withdrawal were assigned at ramdom to double-blind treatment with chlordiazepoxide, chlorpromazine, hydroxyzine, thiamine, or placebo for a period of ten days. They were rated three times daily by nursing personnel using a Nurses' Rating Scale and were asked to complete a Mood Scale daily. Patients generally showed a rapid improvement in different symptom areas regardless of the group to which they had been assigned. Treatment comparisons suggested that fewer symptoms were associated with placebo and thiamine treatment than with the three psychoactive drugs. However, the greater incidence of convulsions and delirium occurring in these two groups as compared with the chlordiazeposide group more than offset any advantage that may exist for what is essentially supportive treatment. |
| Databáze: | OpenAIRE |
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