α-Emitters for Radiotherapy: From Basic Radiochemistry to Clinical Studies—Part 1
Autor: | Sophie Poty, Lynn C. Francesconi, Jason S. Lewis, Michael J. Morris, Michael R. McDevitt |
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Rok vydání: | 2018 |
Předmět: | |
Zdroj: | Journal of Nuclear Medicine. 59:878-884 |
ISSN: | 2159-662X 0161-5505 |
Popis: | With a short particle range and high linear energy transfer, α-emitting radionuclides demonstrate high cell-killing efficiencies. Even with the existence of numerous radionuclides that decay by α-particle emission, only a few of these can reasonably be exploited for therapeutic purposes. Factors including radioisotope availability and physical characteristics (e.g., half-life) can limit their widespread dissemination. The first part of this review will explore the diversity, basic radiochemistry, restrictions, and hurdles of α-emitters. |
Databáze: | OpenAIRE |
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