Metal-free synthesis of aryl esters from carboxylic acids and diaryliodonium salts
| Autor: | Tue B. Petersen, Rehan Khan, Berit Olofsson |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
chemistry.chemical_classification
Steric effects Anions Molecular Structure Carboxylic acid Aryl Organic Chemistry Carboxylic Acids Salt (chemistry) Esters Biochemistry chemistry.chemical_compound Onium Compounds chemistry Metal free Organic chemistry Physical and Theoretical Chemistry Chemoselectivity |
| Zdroj: | Organic letters. 13(13) |
| ISSN: | 1523-7052 |
| Popis: | An efficient arylation of carboxylic acids with diaryliodonium salts has been developed, giving aryl esters in high yields within short reaction times for both aromatic and aliphatic substrates. The transition-metal-free conditions are compatible with a range of functional groups, and good chemoselectivity is observed with unsymmetric diaryliodonium salts. Furthermore, steric hindrance in the ortho positions is well tolerated both in the carboxylic acid and in the diaryliodonium salt, yielding aryl esters that cannot be obtained via other esterification protocols. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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