Transthoracic ultrasonography-guided core needle biopsy of pleural-based lung lesions: prospective randomized comparison between a Tru-cut-type needle and a modified Menghini-type needle
| Autor: | Sergio Sartori, L. Trevisani, I. Nielsen, V. Abbasciano, Paola Tombesi, D. Tassinari |
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| Rok vydání: | 2009 |
| Předmět: |
Thorax
Adult Male medicine.medical_specialty Lung Neoplasms Diagnosis Differential Cytology Biopsy medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies Prospective cohort study Lung Ultrasonography Interventional Aged Aged 80 and over medicine.diagnostic_test business.industry Liver Diseases Ultrasound Biopsy Needle Histology Middle Aged Exact test Female Radiology Differential diagnosis business |
| Zdroj: | Ultraschall in der Medizin (Stuttgart, Germany : 1980). 30(4) |
| ISSN: | 1438-8782 |
| Popis: | PURPOSE: The diagnostic yield of the different types of cutting needles used to perform transthoracic biopsy is scarcely investigated. Aim of the study was to compare a Tru-cut-type (TCT) needle and a modified Menghini-type needle (MMT) in ultrasonography (US)-guided biopsy of pulmonary lesions. MATERIALS AND METHODS: 307 subjects (191 males and 116 females, mean age 58 years) with peripheral lung lesions selected to undergo US-guided biopsy were randomized to undergo biopsy by using an 18-gauge TCT or MMT needle. The specimens were imprinted on two to three slides for cytology and then put into a formalin solution for histology. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and overall accuracy were calculated. Fisher’s exact test was used to compare histology recovery rate (HRR), diagnostic accuracy, and diagnostic yield of the combination of cytology and histology in comparison with cytology alone and histology alone. RESULTS: 155 biopsies were performed using the MMT needle, 152 using the TCT needle. HRR was 112 / 155 (72.3 %) and 144 / 152 (94.7 %), respectively (p < 0.0001). Sensitivity, specificity, PPV, and NPV were 81.6 %, 100 %, 100 %, and 62 % for the former, respectively, and 93.6 %, 100 %, 100 %, and 86 % for the latter. A correct diagnosis was achieved in 133 / 155 biopsies (85.8 %) performed with the MMT needle, and in 145 / 152 biopsies (95.4 %) performed with the TCT needle (p = 0.0041). The combination of cytology and histology had a higher diagnostic yield than cytology alone (p < 0.001) and histology alone (p < 0.001). CONCLUSION: The TCT needle performs better than the MMT needle, and improves the diagnostic accuracy of US-guided transthoracic biopsy of superficial lung lesions. |
| Databáze: | OpenAIRE |
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