Characterization of comorbid PTSD in treatment-seeking alcohol dependent inpatients: Severity and personality trait differences
| Autor: | Joanna R. Sells, Markus Heilig, Melanie L. Schwandt, Laura E. Kwako, Vijay A. Ramchandani, David T. George, Andrew J. Waters |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male 050103 clinical psychology medicine.medical_specialty Poison control Comorbidity Anxiety Toxicology Personality Disorders Severity of Illness Index behavioral disciplines and activities Article Stress Disorders Post-Traumatic 03 medical and health sciences 0302 clinical medicine mental disorders medicine Humans 0501 psychology and cognitive sciences Pharmacology (medical) Psychiatry Neuroticism Pharmacology Inpatients 05 social sciences Alcohol dependence Middle Aged medicine.disease Anxiety Disorders Personality disorders Hospitalization Substance abuse Alcoholism Psychiatry and Mental health Mood Mood disorders Female medicine.symptom Psychology 030217 neurology & neurosurgery Clinical psychology |
| Zdroj: | Drug and Alcohol Dependence. 163:242-246 |
| ISSN: | 0376-8716 |
| DOI: | 10.1016/j.drugalcdep.2016.03.016 |
| Popis: | Background Post-traumatic stress disorder (PTSD) is often comorbid with alcohol dependence (AD), but little is known about the characteristics of AD treatment-seeking inpatients with PTSD. We examined differences between treatment-seeking alcohol dependent inpatients with and without comorbid PTSD. We hypothesized that those with AD and PTSD would have higher levels of: (1) alcohol use and AD severity; (2) anxiety and mood disorders; (3) neuroticism. Methods Individuals ( N = 411, mean age = 41.7 ± 10.0 years) with AD were monitored over 30 days in a suburban inpatient alcohol treatment setting. Patients were evaluated to identify AD and comorbid PTSD, mood and anxiety disorders, alcohol use and dependence severity, personality, and aggression. Results Those with PTSD (19% of the sample) did not differ in the amount of alcohol consumed, but had greater: (1) severity of AD ( p = 0.001, d = 0.44); (2) diagnosis of anxiety ( p = 0.000, OR = 3.64) and mood ( p = 0.000, OR = 4.83) disorders; and (3) levels of neuroticism ( p d = 0.67) and aggression ( p d = 0.81). Conclusions AD patients with comorbid PTSD present a more severe phenotype across AD severity, frequency of anxiety and mood disorders, and levels of neuroticism and aggression. This group may benefit from concurrent treatment of both AD and PTSD. Future research can investigate neuroticism as a potential treatment target. |
| Databáze: | OpenAIRE |
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