Optical Analysis of Reaction Yield and Enantiomeric Excess: A New Paradigm Ready for Prime Time
| Autor: | Samantha L Pilicer, Eric V. Anslyn, Brenden T. Herrera, Christian Wolf, Leo A. Joyce |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Magnetic Resonance Spectroscopy
010402 general chemistry 01 natural sciences Biochemistry Catalysis Mass Spectrometry Colloid and Surface Chemistry Optical imaging Organic Chemicals Particle Size Enantiomeric excess Chromatography High Pressure Liquid Molecular Structure 010405 organic chemistry Chemistry Organic chemicals Extramural Circular Dichroism Optical Imaging Enantioselective synthesis Stereoisomerism General Chemistry 0104 chemical sciences High-Throughput Screening Assays Colorimetry Spectrophotometry Ultraviolet Biochemical engineering |
| Zdroj: | Journal of the American Chemical Society. 140(33) |
| ISSN: | 1520-5126 |
| Popis: | This Perspective highlights the advances of optical methods for asymmetric reaction discovery. Optical analysis allows for the determination of absolute configuration, enantiomeric excess and reaction yield that is amenable to high-throughput experimentation. Thus, the synthetic organic community is encouraged to incorporate the methods discussed to expedite the development of high-yielding, enantioselective transformations. |
| Databáze: | OpenAIRE |
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