Sex Differences in Ambulatory Blood Pressure Levels and Subtypes in a Large Italian Community Cohort

Autor: Stefano Omboni, Nadia A. Khan, Vijay Kunadian, Agnieszka Olszanecka, Aletta E. Schutte, Anastasia S. Mihailidou
Rok vydání: 2023
Předmět:
Zdroj: Hypertension.
ISSN: 1524-4563
0194-911X
DOI: 10.1161/hypertensionaha.122.20589
Popis: BACKGROUND: Sex differences in blood pressure control are recognized. We systematically investigated sex differences in specific components of ambulatory blood pressure (ABP), including variability, day-night changes, morning surge, and hypertension types. METHODS: We analyzed ABPs of 52 911 participants (45.6% male, 54.4% female, 37.0% treated for hypertension) visiting 860 Italian community pharmacies. Sex differences in ABP levels and patterns were evaluated in the whole group and 4 risk groups (antihypertensive-treated patients, patients with diabetes, dyslipidemia, or cardiovascular disease). RESULTS: Average 24-hour, day-time, and night-time blood pressure values were consistently higher in males than females ( P P P P P P CONCLUSIONS: Females show better ABP control than males, but with an increased blood pressure variability and a greater prevalence of white-coat hypertension. These findings support tailored management of hypertension. REGISTRATION: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT03781401
Databáze: OpenAIRE