Wound botulism in injectors of drugs: upsurge in cases in England during 2004
| Autor: | V Mithani, L De Souza-Thomas, M Gent, J Dennis, D Akbulut, Vivian Hope, Jim McLauchlin, Fortune Ncube, Kathie Grant, O Mpamugo, C Ohai |
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| Rok vydání: | 2017 |
| Předmět: |
Reino unido
Grande bretagne medicine.medical_specialty Epidemiology business.industry Public Health Environmental and Occupational Health Botulism medicine.disease medicine.disease_cause Dermatology Botulinum neurotoxin Surgery Wound Botulism England Virology medicine Paralysis Wound Infection Clostridium botulinum Humans medicine.symptom business Substance Abuse Intravenous Royaume uni |
| Zdroj: | Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin. 10(9) |
| ISSN: | 1560-7917 |
| Popis: | Wound infections due to Clostridium botulinum were not recognised in the UK and Republic of Ireland before 2000. C. botulinum produces a potent neurotoxin which can cause paralysis and death. In 2000 and 2001, ten cases were clinically recognised, with a further 23 in 2002, 15 in 2003 and 40 cases in 2004. All cases occurred in heroin injectors. Seventy cases occurred in England; the remainder occurred in Scotland (12 cases), Wales (2 cases) and the Republic of Ireland (4 cases). Overall, 40 (45%) of the 88 cases were laboratory confirmed by the detection of botulinum neurotoxin in serum, or by the isolation of C. botulinum from wounds. Of the 40 cases in 2004, 36 occurred in England, and of the 12 that were laboratory confirmed, 10 were due to type A. There was some geographical clustering of the cases during 2004, with most cases occurring in London and in the Yorkshire and Humberside region of northeast England. |
| Databáze: | OpenAIRE |
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