Diagnostic Value of Serial Measurement of C-Reactive Protein in the Detection of a Surgical Complication after Laparoscopic Bowel Resection for Endometriosis
| Autor: | Lars Maagaard Andersen, Ulrik Schiøler Kesmodel, Mads Riiskjær, Mikkel Seyer-Hansen, Axel Forman, Ken Ljungmann |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Laparoscopic surgery medicine.medical_specialty medicine.medical_treatment Endometriosis Anastomotic Leak Leukocyte Count 03 medical and health sciences Postoperative Complications 0302 clinical medicine Ureter Predictive Value of Tests medicine Humans Postoperative Period Prospective Studies Laparoscopy Colectomy Retrospective Studies 030219 obstetrics & reproductive medicine biology medicine.diagnostic_test business.industry C-reactive protein Obstetrics and Gynecology Bowel resection medicine.disease Surgery C-Reactive Protein medicine.anatomical_structure Reproductive Medicine 030220 oncology & carcinogenesis Predictive value of tests biology.protein Female business Biomarkers |
| Zdroj: | Riiskjær, M, Forman, A, Kesmodel, U S, Andersen, L M, Ljungmann, K & Seyer-Hansen, M 2016, ' Diagnostic Value of Serial Measurement of C-Reactive Protein in the Detection of a Surgical Complication after Laparoscopic Bowel Resection for Endometriosis ', Gynecologic and Obstetric Investigation . https://doi.org/10.1159/000447513 |
| ISSN: | 1423-002X 0378-7346 |
| DOI: | 10.1159/000447513 |
| Popis: | Aims: The study aimed to assess the diagnostic value of serial monitoring of biochemical inflammatory markers (C-reactive protein (CRP) and white blood cell (WBC) count) in the postoperative diagnosis of anastomotic leakage or ureteral injury after bowel resection for deep infiltrating endometriosis. Methods: This is a review of prospectively collected data from 217 patients who underwent laparoscopic bowel resection for endometriosis from January 2009 to April 2015. Patients with an anastomotic leakage or ureteral injury were identified and classified. Results: The frequency of anastomotic leakage requiring reoperation was 8.3%. The frequency of ureteral injury was 4.6%. Median time to diagnosis was 6 days for anastomotic leakage and 8 days for ureteral injury. The daily mean values of serum CRP were significantly higher in patients with a surgical complication starting at the second postoperative day (POD 2, p = 0.004). WBC was significantly higher (p < 0.05) on POD 2 and 3 in patients with a surgical complication. A decrease in CRP from POD 1 to 3 predicted an uncomplicated course in 92.1% of the cases. Conclusion: A decrease in CRP from POD 1 to 3 was an indicator of uncomplicated subsequent postoperative course. The test is recommended when early discharge after rectal resection for deep infiltrating endometriosis is considered. |
| Databáze: | OpenAIRE |
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