Morpho-Functional Alterations in the Gills of a Seawater Teleost, the Ornate Wrasse (Thalassoma pavo L.), after Short-Term Exposure to Chlorpyrifos
| Autor: | Elvira Brunelli, Rachele Macirella, Vittoria Curcio |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Gill
Na+/K+-ATPase Health Toxicology and Mutagenesis Thalassoma pavo Zoology 010501 environmental sciences lcsh:Chemical technology confocal microscopy Toxicology 01 natural sciences Article 03 medical and health sciences chemistry.chemical_compound medicine lcsh:TP1-1185 030304 developmental biology 0105 earth and related environmental sciences 0303 health sciences organophosphorus pesticides Chemical Health and Safety biology seawater fish Aquatic ecosystem gills morphology biology.organism_classification ultrastructure Epithelium medicine.anatomical_structure chemistry Wrasse Chlorpyrifos Ultrastructure |
| Zdroj: | Toxics Volume 8 Issue 4 Toxics, Vol 8, Iss 97, p 97 (2020) |
| ISSN: | 2305-6304 |
| DOI: | 10.3390/toxics8040097 |
| Popis: | Chlorpyrifos (CPF) is an organophosphorus insecticide commonly used for domestic and agricultural purposes. The risk posed by environmental contamination from CPF is well acknowledged, and it has been detected worldwide in aquatic habitats and coastal areas. In addition, due to its slower degradation in seawater compared to freshwater, CPF is of particular concern for marine environments. Here, we investigated for the first time the morpho-functional alterations induced by CPF on the gills of Thalassoma pavo, a widespread species in the Mediterranean Sea. We tested the effects of two sublethal concentrations (4 and 8 µ g/L) after 48 and 96 h. Our study demonstrates that the alterations induced by CPF are dose and time-dependent and highlight the harmful properties of this insecticide. After exposure to the low tested concentration, the more frequent alteration is an intense proliferation of the primary epithelium, whereas after exposure to the high concentration, the primary epithelium proliferation is less extensive, and the most evident effects are the thinning of secondary lamellae and the ectopia of chloride and goblet cells. CPF also modulated the expression of Na+/K+-ATPase. Dilation of lamellar apical tips, pillar cell degeneration, and appearance of aneurysms are often observed. |
| Databáze: | OpenAIRE |
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