Rhinosinusitis: developing guidance for clinical trials
| Autor: | Jens U. Ponikau, Melvyn R. Danzig, Raymond G. Slavin, Daniel L. Hamilos, Mark S. Schubert, Robert M. Naclerio, Allen Adinoff, Bradley F. Marple, Stephen G. Jenkins, Valerie J. Lund, James A. Hadley, Vernon M. Chinchilli, Michael G. Stewart, Larry Borish, Berrylin J. Ferguson, Ellen R. Wald, Claus Bachert, Birgit Winther, Alkis Togias, Ruby Pawankar, Mahmood F. Mafee, Donald C. Lanza, Richard A. Nicklas, W. J. Fokkens, Eli O. Meltzer |
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| Rok vydání: | 2006 |
| Předmět: |
Pathology
medicine.medical_specialty Chronic rhinosinusitis Immunology MEDLINE Health outcomes 03 medical and health sciences 0302 clinical medicine Nasal Polyps Quality of life medicine otorhinolaryngologic diseases Immunology and Allergy Humans Nasal polyps Sinusitis 030223 otorhinolaryngology Intensive care medicine Rhinitis Clinical Trials as Topic medicine.diagnostic_test business.industry Clinical study design Endoscopy medicine.disease Surgery Clinical trial Upper respiratory tract infection Clinical research Otorhinolaryngology 030220 oncology & carcinogenesis Chronic Disease business |
| Zdroj: | The Journal of allergy and clinical immunology. 118 |
| ISSN: | 0091-6749 |
| Popis: | The Rhinosinusitis Initiative was developed by 5 national societies. The current guidance document is an expansion of the 2004 publication, "Rhinosinusitis: Establishing definitions for clinical research and patient care" and provides templates for clinical trials in antimicrobial, anti-inflammatory, and symptom-relieving therapies for the following: (1) acute presumed bacterial rhinosinusitis, (2) chronic rhinosinusitis (CRS) without nasal polyps, (3) CRS with nasal polyps, and (4) classic allergic fungal rhinosinusitis. In addition to the templates for clinical trials and proposed study designs, the Rhinosinusitis Initiative has developed 6 appendices, which address (1) health outcomes, (2) nasal endoscopy and staging of CRS, (3) radiologic imaging, (4) microbiology, (5) laboratory measures, and (6) biostatistical methods. |
| Databáze: | OpenAIRE |
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