Autotransfusion of hemothorax blood in trauma patients: is it the same as fresh whole blood?
| Autor: | John D. Olson, Chantal R. Harrison, Ronald M. Stewart, Michael G. Corneille, Joel E. Michalek, Russell A. Higgins, Marc A. Salhanick, Daniel L. Dent |
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| Rok vydání: | 2011 |
| Předmět: |
Male
medicine.medical_specialty Blood transfusion medicine.medical_treatment Fibrinogen Blood Transfusion Autologous Internal medicine medicine Humans Prospective Studies Whole blood Hemothorax Hematology medicine.diagnostic_test business.industry General Medicine Venous blood Middle Aged medicine.disease Treatment Outcome Anesthesia Drainage Wounds and Injuries Female Partial Thromboplastin Time Surgery business Partial thromboplastin time medicine.drug Autotransfusion |
| Zdroj: | The American Journal of Surgery. 202:817-822 |
| ISSN: | 0002-9610 |
| DOI: | 10.1016/j.amjsurg.2011.06.043 |
| Popis: | Autotransfusable shed blood has been poorly characterized in trauma and may have similarities to whole blood with additional benefits.This was a prospective descriptive study of adult patients from whom ≥50 mL of blood was drained within the first 4 hours after chest tube placement. Pleural and venous blood samples were analyzed for coagulation, hematology, and electrolytes.Twenty-two subjects were enrolled in 9 months. The following measured coagulation factors of hemothorax were significantly depleted compared with venous blood: international normalized ratio (9 in contrast to 1.1, P.001), activated partial thromboplastin time (180 in contrast to 28.5 seconds, P.001), and fibrinogen (50 in contrast to 288 mg/dL, P.001). The mean hematocrit (26.4 in contrast to 33.9), (P = .003), hemoglobin (9.3 in contrast to 11.8 g/dL, P = .004), and platelet count (53 in contrast to 174 K/μL, P.001) of hemothorax were significantly lower than venous blood. A hemothorax volume of 726 mL was calculated to be equivalent to 1 U of red blood cells.Hemothorax blood contains significantly decreased coagulation factors and has lower hemoglobin when compared with venous blood. |
| Databáze: | OpenAIRE |
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