Long-term Quality of Life Following Vestibular Schwannoma Excision Via the Translabyrinthine Approach

Autor: Osama Mahmoud, Richard T. Ramsden, Andrew T. King, Scott A. Rutherford, Stephen J. Broomfield, Jack S. Nicholson, Ashish K. Mandavia
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Adult
Male
Quality of life
medicine.medical_specialty
Neurofibromatosis 2
Time Factors
Cross-sectional study
Population
Audiology
Schwannoma
Tertiary Care Centers
03 medical and health sciences
0302 clinical medicine
Surveys and Questionnaires
medicine
Humans
Acoustic neuroma (vestibular schwannoma)
Neurofibromatosis type 2
030223 otorhinolaryngology
education
Social Behavior
Aged
Retrospective Studies
education.field_of_study
Translabyrinthine approach
business.industry
Incidence (epidemiology)
Retrospective cohort study
Acoustics
Neuroma
Acoustic

Middle Aged
medicine.disease
humanities
Sensory Systems
Cross-Sectional Studies
Mental Health
Treatment Outcome
Otorhinolaryngology
Physical therapy
Quality of Life
Female
Surgery
Neurology (clinical)
business
030217 neurology & neurosurgery
Neurilemmoma
Zdroj: Broomfield, S J, Mandavia, A K, Nicholson, J S, Mahmoud, O, King, A T, Rutherford, S A & Ramsden, R T 2017, ' Long-term Quality of Life Following Vestibular Schwannoma Excision Via the Translabyrinthine Approach ', Otology and Neurotology, vol. 38, no. 8, pp. 1165-1173 . https://doi.org/10.1097/MAO.0000000000001507
DOI: 10.1097/MAO.0000000000001507
Popis: Objective: To assess post-operative quality of life (QOL) and other patient-reported outcomes following surgery for vestibular schwannoma.Study Design: Cross-sectional retrospective case review using postal questionnaires.Setting: Tertiary referral centre.Patients: Five hundred consecutive patients undergoing surgery for vestibularschwannoma.Intervention(s): Patients undergoing surgery via the translabyrinthine approach(excluding neurofibromatosis type 2) under the senior author, with a minimum of five years follow-up, were included.Main Outcome Measure(s): QOL was assessed using the Short Form 36 (SF-36)questionnaire and a disease-specific survey to assess patients' subjective outcomes.Results: The SF-36 scores in this group were significantly lower than the general UK population, though 24% of respondents reported a subjective improvement in overall QOL. Tumours larger than 4cm were related to a reduced SF-36 total mental component score (P = 0.037). Increased age at time of surgery correlated with a reduced physical component of QOL (correlation coefficient = -0.26) and an improved mental component (correlation coefficient = 0.26). Subjective reports of post-operative symptoms and return to work, driving and social activities were similar to other published studies. 35% of patients reported vivid dreams or nightmares following surgery; the first reported incidence of this phenomenon in a large group of vestibular schwannoma patients.Conclusions: Generic measures of QOL in patients following translabyrinthine surgery for vestibular schwannoma do not always match subjective reports, reflecting the complexity of QOL assessment and the range of outcomes in this group. Increased time since surgery appears to be associated with an improvement in mental health.
Databáze: OpenAIRE