Validation of four single-item patient-reported assessments of sleep in adult atopic dermatitis patients
| Autor: | Vivek Singam, Ryan Sacotte, Robert Kantor, Sherief R. Janmohamed, Sylvie Gabriel, Derek Y. Hsu, Donald Lei, Supriya Immaneni, Muhammad Yousaf, Rajeev Chavda, Jonathan I. Silverberg, Kevin R. Patel, Rishi Chopra, Paras P Vakharia |
|---|---|
| Přispěvatelé: | Dermatology, Skin function and permeability |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Sleep Wake Disorders Pulmonary and Respiratory Medicine medicine.medical_specialty Adolescent Concordance Concurrent validity Immunology Eczema Area and Severity Index Dermatitis Atopic Young Adult 03 medical and health sciences 0302 clinical medicine Surveys and Questionnaires medicine Humans Immunology and Allergy Public Health Surveillance Patient Reported Outcome Measures Prospective Studies 030212 general & internal medicine SCORAD skin and connective tissue diseases Aged Aged 80 and over medicine.diagnostic_test business.industry Pruritus Discriminant validity Reproducibility of Results Dermatology Life Quality Index Atopic dermatitis Middle Aged medicine.disease 030228 respiratory system Convergent validity Quality of Life Physical therapy Female Self Report Sleep business |
| Popis: | The optimal approaches for monitoring sleep disturbances in adults with atopic dermatitis (AD) is not established. Multiple patient-reported outcome measures for AD and itch have sleep-related items. These items have not been validated previously.Assess the measurement properties of sleep-related items from the Patient-Oriented Eczema Measure (POEM), SCORing AD (SCORAD), 5-dimensions of itch (5D), and ItchyQOL in adults with AD.We performed a prospective dermatology practice-based study using questionnaires and evaluation by a dermatologist (n = 115).There was modest overlap and weak-moderate concordance of responses to the different assessments. Regarding concurrent validity, POEM-sleep, SCORAD-sleep, 5D-sleep, and ItchyQOL-sleep showed moderate correlations with each other. Regarding convergent validity, all items showed moderate correlation with total POEM, but weak correlations with Eczema Area and Severity Index (EASI), objective and total SCORAD, moderate to strong correlations with mean ItchyQOL and Dermatology Life Quality Index (DLQI), but poor or no significant correlation with Numeric Rating Scale (NRS) for worst or average itch. Regarding discriminant validity, all items showed significant and stepwise increases with increasing self-reported and physician-reported AD severity (Kruskal-Wallis, P.01 for all). Floor effects were observed for POEM-sleep (n = 53, 46.1%), SCORAD-sleep (n = 28, 24.4%), 5D-sleep (n = 41, 35.7%), and ItchyQOL-sleep (n = 33, 28.7%); no ceiling effects were observed. Change in sleep-related item scores showed moderate strong correlations with change in POEM, 5Ditch, mean ItchyQOL, DLQI, objective and total SCORAD, and EASI, but inconsistent correlations with change of itch severity.Sleep-related items from POEM, SCORAD, 5D and ItchyQOL showed good validity and responsiveness to monitor sleep disturbances in adult AD patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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