Sinusitis and Pneumonia Hospitalization After Introduction of Pneumococcal Conjugate Vaccine
| Autor: | Tobias Alfvén, Lina Schollin Ask, Margareta Eriksson, Rutger Bennet, Ann Lindstrand, Ilias Galanis, Malin Ryd Rinder, Birgitta Henriques-Normark, Margareta Blennow, Sofia Hultman Dennison, Åke Örtqvist |
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| Rok vydání: | 2014 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Heptavalent Pneumococcal Conjugate Vaccine Adolescent medicine.disease_cause Lower risk Pneumococcal Infections Pneumococcal conjugate vaccine Pneumococcal Vaccines Streptococcus pneumoniae medicine Humans Sinusitis Child Sweden Vaccines Conjugate business.industry Infant Newborn Infant Pneumococcal 7-Valent Conjugate Vaccine Pneumonia Pneumococcal medicine.disease Empyema Hospitalization Vaccination Pneumonia Cross-Sectional Studies Child Preschool Pediatrics Perinatology and Child Health Female business medicine.drug |
| Zdroj: | Pediatrics. 134:e1528-e1536 |
| ISSN: | 1098-4275 0031-4005 |
| DOI: | 10.1542/peds.2013-4177 |
| Popis: | BACKGROUND AND OBJECTIVE: Streptococcus pneumoniae is a major cause of pneumonia and sinusitis. Pneumonia kills >1 million children annually, and sinusitis is a potentially serious pediatric disease that increases the risk of orbital and intracranial complications. Although pneumococcal conjugate vaccine (PCV) is effective against invasive pneumococcal disease, its effectiveness against pneumonia is less consistent, and its effect on sinusitis is not known. We compared hospitalization rates due to sinusitis, pneumonia, and empyema before and after sequential introduction of PCV7 and PCV13. METHOD: All children 0 to RESULTS: Hospitalizations for sinusitis decreased significantly in children aged 0 to CONCLUSIONS: PCV7 and PCV13 vaccination led to a 66% lower risk of hospitalization for sinusitis and 19% lower risk of hospitalization for pneumonia in children aged 0 to |
| Databáze: | OpenAIRE |
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