Reliability of the lung to thorax transverse area ratio as a predictive parameter in fetuses with congenital diaphragmatic hernia
| Autor: | Mari Saito, Motoyoshi Kawataki, Haruhiko Sago, Hajime Takayasu, Noriaki Usui, Hiroomi Okuyama, Nobuyuki Morikawa, Tomoo Nakamura, Hiroshi Ishikawa, Kouji Masumoto, Noboru Inamura, Yoshihiro Kitano, Keisuke Nose, Satoshi Hayashi |
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| Rok vydání: | 2010 |
| Předmět: |
Male
Thorax medicine.medical_specialty Diaphragmatic breathing Gestational Age Prenatal diagnosis Sensitivity and Specificity Severity of Illness Index Ultrasonography Prenatal Cohort Studies Fetal Organ Maturity Predictive Value of Tests Pregnancy Humans Medicine Hernia Lung Retrospective Studies Hernia Diaphragmatic business.industry Reproducibility of Results Gestational age Congenital diaphragmatic hernia General Medicine respiratory system medicine.disease Survival Analysis respiratory tract diseases Surgery Fetal Diseases medicine.anatomical_structure ROC Curve Predictive value of tests Pediatrics Perinatology and Child Health Female Radiology Hernias Diaphragmatic Congenital business |
| Zdroj: | Pediatric Surgery International. 27:39-45 |
| ISSN: | 1437-9813 0179-0358 |
| DOI: | 10.1007/s00383-010-2725-z |
| Popis: | An accurate prenatal assessment of the patients' severity is essential for the optimal treatment of individuals with congenital diaphragmatic hernia (CDH). The purpose of this study was to clarify the reliability of the lung to thorax transverse area ratio (L/T) as a prenatal predictive parameter.A multicenter retrospective cohort study was conducted on 114 isolated CDH fetuses with a prenatal diagnosis during the period between 2002 and 2007 at five participating centers in Japan. The relationship between the gestational age and the L/T was analyzed. The most powerful measurement point and accurate cutoff value of the L/T was determined by an analysis of a receiver operating characteristic curve, which was verified by comparing the patients' severity.There was a negative correlation between the gestational age and the L/T in the non-survivors, and no correlation in the survivors. There were significant differences in the parameters which represented the patients' severity including the respiratory and circulatory status, the surgical findings, and the final outcomes between the groups divided at 0.080 in the minimum value of the L/T during gestation.The L/T was not strongly influenced by the gestational age, and it was found to be a reliable prenatal predictive parameter in fetuses with isolated CDH. |
| Databáze: | OpenAIRE |
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