Neurogenic bladder in patients with traumatic spinal cord injury: treatment and follow-up

Autor: Ebru Alemdaroğlu, Ayşenur Bardak, Ece Çınar, Bilge Yilmaz, N Catalbaş, Hakan Tunç, Yesim Akkoc, Yasin Demir, Murat Ersöz, Seçilay Güneş, Kurtuluş Köklü, Berrin Gündüz, Ridvan Alaca, Hale Karapolat, Haydar Gök, Necmettin Yildiz, I Turna, Belgin Erhan
Přispěvatelé: Ege Üniversitesi
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Questionnaires
Male
intermittent catheterization
spinal cord lesion
retrospective study
urologic and male genital diseases
Cholinergic Antagonists
Adolescent
Adult
Aged
Cholinergic Antagonists/therapeutic use
Cross-Sectional Studies
Female
Follow-Up Studies
Humans
Intermittent Urethral Catheterization
Middle Aged
Retrospective Studies
Sex Factors
Spinal Cord Injuries/drug therapy/*physiopathology/*rehabilitation
Surveys and Questionnaires
Treatment Outcome
Urinary Bladder
Neurogenic/drug therapy/*physiopathology/*rehabilitation

Urinary Tract Infections/drug therapy/physiopathology
Young Adult
middle aged
cholinergic receptor blocking agent
bladder training
indwelling catheter
pathophysiology
media_common
fever
solifenacin
Urinary bladder
adult
medical specialist
trospium chloride
article
neurogenic bladder
clinical trial
General Medicine
condom catheter
oxybutynin
female genital diseases and pregnancy complications
aged
female
medicine.anatomical_structure
priority journal
Neurology
Urinary Tract Infections
quadriplegia
young adult
disease severity
Propiverine
Tolterodine
medicine.drug
adult diaper
medicine.medical_specialty
sex difference
media_common.quotation_subject
Urinary system
bacteriuria
Bacteriuria
Urination
urethral catheter
paraplegia
Internal medicine
medicine
cross-sectional study
follow up
human
Urinary Bladder
Neurogenic

Oxybutynin
micturition
Spinal Cord Injuries
drug use
Solifenacin
business.industry
questionnaire
asymptomatic bacteriuria
medicine.disease
propiverine
tolterodine
major clinical study
urethral catheterization
spinal cord injury
multicenter study
Neurology (clinical)
botulinum toxin A
darifenacin
urinary tract infection
business
ISSN: 0003-3723
Popis: WOS: 000337233100009
PubMed ID: 24732167
Study design: Multi-center, cross-sectional study. Objectives: Our aim was to evaluate the treatment methods and follow-up of neurogenic bladder in patients with traumatic spinal cord injury retrospectively using a questionnaire. Setting: Turkey. Methods: Three hundred and thirty-seven patients who had spinal cord injury for at least 2 years were enrolled from six centers in the neurogenic bladder study group. They were asked to fill-out a questionnaire about treatments they received and techniques they used for bladder management. Results: The study included 246 male and 91 female patients with a mean age of 42 +/- 14 years. Intermittent catheterization (IC) was performed in 77.9% of the patients, 3.8% had indwelling catheters, 13.8% had normal spontaneous micturition, 2.6% performed voiding maneuvers, 1.3% used diapers and 0.6% used condom catheters. No gender difference was found regarding the techniques used in bladder rehabilitation (P > 0.05). Overall, 63.2% of patients used anticholinergic drugs; anticholinergic drug use was similar between genders (P > 0.05). The most common anticholinergic drug used was oxybutynin (40.3%), followed by trospium (32.6%), tolterodine (19.3%) darifenacin (3.3%), propiverine (3.3%) and solifenacin (1.1%). The specialties of the physicians who first prescribed the anticholinergic drug were physiatrists (76.2%), urologists (22.1%) and neurologists (1.7%). Only four patients had previously received injections of botulinum-toxin-A into the detrusor muscle and three of them stated that their symptoms showed improvement. Most of the patients (77%) had regular follow-up examinations, including urine cultures, urinary system ultrasound and urodynamic tests, when necessary; the reasons for not having regular control visits were living distant from hospital (15.3%) and monetary problems (7.7%). Of the patients, 42.7% did not experience urinary tract infections (UTI), 36.4% had bacteriuria but no UTI episodes with fever, 15.9% had 1-2 clinical UTI episodes per year and 5% had >= 3 clinical UTIs. The clinical characteristics of patients with and without UTI (at least one symptomatic UTI during 1 year) were similar (P40.05). The frequency of symptomatic UTI was similar in patients using different bladder management techniques (P > 0.05). Conclusion: The most frequently used technique for bladder rehabilitation in patients with SCI was IC (77.9%). In all, 63.2% of patients used anticholinergic drugs, oxybutynin being the most commonly used drug. Also, 77% of patients had regular control visits for neurogenic bladder; 42.7% did not experience any UTIs.
Databáze: OpenAIRE