Estimation of cardiac output in man by dye dilution method using an automatic computing oximeter

Autor: Paul Sekelj, Arnold L. Johnson, Wanda Jegier, D.V. Bates
Rok vydání: 1958
Předmět:
Zdroj: American Heart Journal. 55:810-823
ISSN: 0002-8703
DOI: 10.1016/0002-8703(58)90098-x
Popis: Estimation of cardiac output by the dye dilution method with an automatic computing oximeter is described. This instrument provides a quantitative and continuous measurement of the arterial concentration of Evans blue T-1824 dye, by performing a computation of the data obtained from the ear by means of a photoelectric earpiece. This method has the obvious advantage of doing away with the necessity of collecting and analyzing blood samples for the purpose of calibrating individual dye dilution curves. Other advantages of the method and the procedure to determine the instrument constant for cardiac output are discussed. Studies in normal subjects show a close correlation between the cardiac output estimates based on the automatically computed dye concentration values and those obtained by calculation from the instrument readings. Satisfactory agreement is found between the nearly simultaneous estimates obtained by the direct Fick procedure and by this method, using a single calibrating factor for all subjects. The sensitivity and the dynamic response characteristics of the system appear to be adequate for several consecutive determinations of cardiac output when small quantities of dye (about 0.2 mg./Kg. per injection) are used.
Databáze: OpenAIRE