Containing Carbapenemase-producing Klebsiella pneumoniae in an endemic setting

Autor: Vivi Miriagou, Vana Sypsa, Leonidas S. Tzouvelekis, George L. Daikos, Kalliopi Spyridopoulou, Mina Psichogiou, Amalia Karapanou, Linos Hadjihannas
Jazyk: angličtina
Rok vydání: 2020
Předmět:
0301 basic medicine
Microbiology (medical)
medicine.medical_specialty
Endemic Diseases
Klebsiella pneumoniae
media_common.quotation_subject
030106 microbiology
Infection control
Drug resistance
Active surveillance
030501 epidemiology
beta-Lactamases
lcsh:Infectious and parasitic diseases
Tertiary Care Centers
03 medical and health sciences
Medical microbiology
Bacterial Proteins
Hygiene
Internal medicine
Hospital-acquired infection
Prevalence
medicine
Humans
Pharmacology (medical)
Colonization
lcsh:RC109-216
media_common
Cross Infection
Greece
biology
business.industry
Research
Incidence (epidemiology)
Public Health
Environmental and Occupational Health
biology.organism_classification
medicine.disease
Carbapenemases
Anti-Bacterial Agents
Klebsiella Infections
Infectious Diseases
Carbapenems
0305 other medical science
business
Zdroj: Antimicrobial Resistance and Infection Control, Vol 9, Iss 1, Pp 1-9 (2020)
Antimicrobial Resistance and Infection Control
ISSN: 2047-2994
Popis: Background Carbapenemase-producing K. pneumoniae (CP-Kp) has been established as important nosocomial pathogen in most tertiary care hospitals in Greece. The aim of the present study was to examine the impact of an enhanced infection control program on the containment of CP-Kp in a haematology unit where the incidence of CP-Kp infections was high. Methods The study was conducted from June 2011 to December 2014 in a haematology unit of a tertiary-care 500-bed hospital located in Athens, Greece. A bundled intervention (active surveillance cultures, separation of carriers from non-carriers, assignment of dedicated nursing staff, contact precautions, environmental cleaning, and promotion of hand hygiene) was tested whether would reduce colonization and infection caused by CP-Kp. Results A total of 2507 rectal swabs were obtained; 1199 upon admission from June 2011 to June 2013 and 1307 during hospitalization from June 2011 to December 2012. During intervention the admission prevalence of CP-Kp colonization (p
Databáze: OpenAIRE
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