Insulin Aspart–Induced Lipoatrophy Treated Successfully With Glucocorticoid Injection
| Autor: | Subhankar Chowdhury, Arijit Singha, Sudipta Saha, Hridish N. Chakravarti, Rana Bhattacharjee, Sujoy Ghosh, Ranajit Bari, Dibakar Biswas |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
business.industry Insulin medicine.medical_treatment Type 2 Diabetes Mellitus 030209 endocrinology & metabolism General Medicine medicine.disease RC648-665 Diseases of the endocrine glands. Clinical endocrinology Insulin aspart 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Endocrinology Internal medicine medicine Abdomen Betamethasone business Lipoatrophy Glucocorticoid Glycemic medicine.drug |
| Zdroj: | AACE Clinical Case Reports, Vol 3, Iss 3, Pp e187-e189 (2017) |
| ISSN: | 2376-0605 |
| Popis: | Objective: To evaluate the management of insulin-induced lipoatrophic areas with local subcutaneous glucocorticoid injection.Methods: A 42-year-old woman with type 2 diabetes mellitus, who was taking biphasic insulin aspart for the last 3 years, presented with two areas of lipoatrophy of insulin injection sites on the anterior abdominal wall. It was associated with erratic glycemic control. We administered glucocorticoid injections (betamethasone) subcutaneously without mixing with insulin on the right-sided lipoatrophic area of the abdomen. The left-sided lesion served as a control.Results: After 6 weeks of treatment, lipoatrophy on the right side of the abdomen showed significant improvement in comparison to the left side, which was also documented by magnetic resonance imaging. Glycemic status was also improved.Conclusion: We observed significant improvement of lipoatrophy with glucocorticoid injection. Contrary to previous observations, betamethasone did not adversely affect the glycemic status. Furthermore, insulin requirement was also decreased. |
| Databáze: | OpenAIRE |
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