Low Prevalence of Extraesophageal Gastrointestinal Pathology in Patients with Eosinophilic Esophagitis
| Autor: | Nirmala Gonsalves, Ikuo Hirano, Guang Yu Yang, Brent Hiramoto, Dyanna L. Gregory, Nancy Ho, Angelika Zalewski |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Abdominal pain medicine.medical_specialty Physiology Gastroenterology Endoscopy Gastrointestinal 03 medical and health sciences 0302 clinical medicine Duodenitis Internal medicine Eosinophilia medicine Eosinophilic gastroenteritis Prevalence Humans Esophagus Eosinophilic esophagitis Retrospective Studies biology business.industry Stomach Gastrointestinal pathology Eosinophilic Esophagitis Helicobacter pylori medicine.disease biology.organism_classification Enteritis Celiac Disease medicine.anatomical_structure 030220 oncology & carcinogenesis Gastritis 030211 gastroenterology & hepatology medicine.symptom business |
| Zdroj: | Digestive diseases and sciences. 67(7) |
| ISSN: | 1573-2568 |
| Popis: | Limited data are available to support current guidelines recommendations on obtaining gastric and duodenal biopsies of patients with clinical and histologic manifestations consistent with eosinophilic esophagitis (EoE) to rule out eosinophilic gastritis (EG) or duodenitis (EoD). Our study examined the prevalence of concomitant extraesophageal, gastrointestinal pathology to better characterize the diagnostic yield of additional biopsies. This was a single-center, retrospective study which utilized ICD 9 codes (530.13) and search queries of pathology reports (“Eosinophilic esophagitis,” “EoE”) to identify EoE patients. Patient endoscopy reports, pathology reports, and office notes were manually reviewed to characterize cases. The electronic health record search yielded 1,688 EoE adults. In those who had extra-esophageal biopsies obtained, EG was identified in 34 (3.4%), H. pylori in 45 (4.6%), EoD in 27 (3.3%), and histology consistent with celiac disease in 20 (2.5%). Endoscopic abnormalities were found in the stomach of 92% of patients with EoE and EG and in the duodenum of 50% of patients with EoE and EoD. Symptoms of dyspepsia and/or abdominal pain occurred in a significantly greater proportion of patients with extraesophageal disease (64% vs. 19% in EoE group, p |
| Databáze: | OpenAIRE |
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