Popis: |
BackgroundHuman body infection with V. vulnificus, especially for patients with some chronic diseases, can cause severe wound infections, septic shock and necrotizing fasciitis of skin and muscle, which in turn can lead to multiple organ failure. Vibrio vulnificus infection patients are more common in our country coastal areas and military activities, but there have been very rare reports successful treatment and limb salvage patients.Case presentation:A 46-year-old male with no disease history was admitted to our emergency department with a diagnosis of severe fever caused by an accidental stab wound. The results of infection was V. vulnificus. Physical examination revealed that his right upper limb was severely inflamed with ecchymosis and several blisters. We would have an emergency operation on his right forearm incision. A 60-year-old female with a history of gout and rheumatic heart disease was admitted to our emergency department with a diagnosis of severe fever with bacteraemia. The initial diagnosis was severe septic shock and right forearm compartment syndrome. The results of high-throughput sequencing indicated V. vulnificus. The patient was transferred to the intensive care unit for treatment after the operation. They recovered without limb salvage. We review the pathogenetic mechanism, epidemiology, clinical characteristics, and treatment of this infection.ConclusionsWhen Vibrio vulnificus patients develop bacteraemia and necrotizing fasciitis symptoms,emergency surgical debridement combined with anti-infection therapy should be considered. |