Embryonal rhabdomyosarcoma of the cervix presenting as a cervical polyp in a 16-year-old adolescent: a case report
| Autor: | L. Chbani, Naoufal Mellas, Imane Kamaoui, Khalid Hassouni, Hakima Bouguern, Fatima Zohra Fdili, Hikmat Chaara, Sofia Jayi, Touria Bouhafa, My Abdelilah Melhouf, S. Arifi, Imane Hafidi, Afaf Laamarti, Siham Tizniti |
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| Jazyk: | angličtina |
| Předmět: |
medicine.medical_specialty
Cervical polyp Adolescent medicine.medical_treatment Uterine Cervical Neoplasms Case Report Prognostic factors Cervix Polyps medicine Humans Rhabdomyosarcoma Embryonal Radical surgery Rhabdomyosarcoma Gynecology Medicine(all) Hysterectomy business.industry General Medicine medicine.disease Polypectomy Management medicine.anatomical_structure Vagina Female Embryonal rhabdomyosarcoma Radiology business |
| Zdroj: | Journal of Medical Case Reports |
| ISSN: | 1752-1947 |
| DOI: | 10.1186/1752-1947-8-241 |
| Popis: | Introduction Embryonal rhabdomyosarcoma of the female genital tract is rare in the cervix. It has been mainly discussed in the context of individual case studies. It tends to occur in children and young women. Treatment ranges from radical surgery to conservative surgery, followed by chemotherapy. Case presentation A 16-year-old Moroccan adolescent girl presented to our center with a protruding mass from her vaginal introitus, as a polyp of 6cm. An examination revealed a polyp within her vagina, thought to be arising from her cervix and a polypectomy was performed. Microscopic findings are consistent with an embryonal rhabdomyosarcoma (botryoide type). A computed tomography of her thorax, abdomen and pelvis were performed and residual disease was found as a mass located at her cervix, which measured approximately 4.5cm in its widest dimensions, without evidence of metastatic disease. Due to the fact that she is young, after discussions in a multidisciplinary meeting, she was subsequently treated with four cycles of multi-agent chemotherapy. Two cycles of chemotherapy and radiotherapy were administered due to the lack of response, but she presented vaginal bleeding with persistence of the same mass in computed tomography. Hence a total interadnexal hysterectomy was made. A histologic examination found residual embryonal rhabdomyosarcoma (botryoide type) located in all her cervix and she is currently under chemotherapy. Conclusions The presence of a cervical polyp in an adolescent is a gynecologic oddity and must necessarily be examined histologically because it might be a rhabdomyosarcoma. This is extremely important because diagnosis at an early stage of the disease is a highly favorable prognostic factor that allows “fertility-sparing surgery” for these young patients. |
| Databáze: | OpenAIRE |
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