Long-term (≥10 years) results of corneal endothelial cell loss after cataract surgery
| Autor: | Jung Yeol Choi, Young Keun Han |
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| Rok vydání: | 2018 |
| Předmět: |
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medicine.medical_specialty Visual acuity genetic structures Endothelium medicine.medical_treatment Visual Acuity After cataract Intraocular lens Cell Count Cataract Extraction Postoperative Complications medicine Outpatient clinic Humans Aged Retrospective Studies Aged 80 and over business.industry Endothelium Corneal Retrospective cohort study General Medicine Cataract surgery Corneal Endothelial Cell Loss Middle Aged eye diseases Surgery Endothelial stem cell Ophthalmology medicine.anatomical_structure Female sense organs medicine.symptom business Follow-Up Studies Forecasting |
| Zdroj: | Canadian journal of ophthalmology. Journal canadien d'ophtalmologie. 54(4) |
| ISSN: | 1715-3360 |
| Popis: | Objective To investigate the extent of long-term corneal endothelial loss after uneventful cataract surgery and the factors associated with decreases in corneal endothelial cell density (ECD). Design Retrospective case series. Participants Patients who had undergone uncomplicated cataract surgery. Methods This study comprised 81 eyes of 48 patients who had undergone cataract surgery >10 years previously by a single surgeon with the same intraocular lens and visited the outpatient clinic between January 2014 and February 2017. Long-term (≥10 years) changes in visual outcome and ECD after uncomplicated cataract surgery were evaluated. To analyze factors correlated with endothelial cell loss, preoperative biometric variables, including cataract grade, anterior chamber depth, axial length, and postoperative corneal edema, were evaluated. Results The mean ± SD preoperative and long-term postoperative ECD was 2793 ± 351.09 and 2148 ± 478.38 cells/mm2, respectively. The mean follow-up period was 11.08 ± 1.06 years and 10-year ECD loss rate was 20.62 ± 13.63%. Preoperative nuclear firmness was most statistically correlated with 10-year ECD loss (β-coefficient 0.394 [95% CI 3.402–9.448]; p Conclusion Preoperative nuclear firmness and postoperative corneal edema were predictors of long-term (≥10 years) endothelial cell loss and severe endothelial cell loss after cataract surgery. It is important to remember that eyes with increased nuclear firmness have a significantly higher risk of long-term enhanced ECL. |
| Databáze: | OpenAIRE |
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